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an·guish Listen to audio/ˈæŋgwɪʃ/ noun
[noncount] : extreme suffering, grief, or pain
tears/cries of anguish He experienced the anguish of divorce after 10 years of marriage. mental anguish They watched in anguish as fire spread through the house.
— an·guished Listen to audio /ˈæŋgwɪʃt/ adjective [more anguished; most anguished]
She looked at me with an anguished expression. I will never forget their anguished cries.

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